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Home » Blog » Rabies Infection Linked To Organ Transplant
World

Rabies Infection Linked To Organ Transplant

Ella Thompson
Last updated: December 13, 2025 9:35 pm
Ella Thompson
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A rare rabies infection tied to an organ transplant has prompted urgent reviews of donor screening and post-exposure care, according to health authorities. Officials say the donor was scratched by an animal before death, and the infection appears to have passed through transplanted tissue to a recipient. Investigators are tracing contacts, notifying transplant centers, and evaluating whether earlier treatment might have prevented the outcome.

Contents
What Investigators ReportHow Rabies Can Spread Through TransplantsPast Cases and Known RisksWhat Health Officials Advise NowExpert Views and Next StepsWhat To Watch

Rabies is almost always fatal once symptoms appear. The virus is commonly spread through saliva from bites, and more rarely, scratches if contaminated with saliva from an infected animal. The case is renewing questions about how transplant programs assess donor risk when a recent animal exposure is reported or suspected.

What Investigators Report

“Organ infected with rabies after man was scratched by animal.”

The initial account suggests the donor sustained a scratch from an animal before the organ was recovered. It is unclear which organ was involved or how many recipients were affected. Health departments and transplant organizations have started a standard traceback to identify recipients, review donor history, and alert hospitals that may have handled the case.

Clinicians told reporters they will look for any signs of neurological illness in recipients and consider immediate post-exposure prophylaxis for anyone at risk. Timing matters with rabies. If vaccines and immune globulin are given before symptoms start, they can stop the virus from taking hold.

How Rabies Can Spread Through Transplants

Rabies travels from the site of exposure along nerves to the brain. Once there, it causes fever, confusion, anxiety, tingling, trouble swallowing, and, later, coma. Because the incubation period can range from weeks to months, a person can carry the virus without obvious signs.

Routine donor screening does not include broad rabies testing because the disease is so rare. Transplant teams rely on medical history, physical exams, and any red flags such as unexplained encephalitis, recent animal exposures, or odd behavior that might suggest infection. In this case, the reported animal scratch raises concern that contaminated tissue carried the virus into a recipient.

Past Cases and Known Risks

Transplant-linked rabies transmission has occurred before, although it is very uncommon. In past U.S. investigations, single donors infected multiple recipients because no one suspected rabies at the time of donation. Those cases led to revised guidance that stresses careful review of donors with unexplained neurological illness or recent wildlife exposures.

Human rabies cases in the United States number in the low single digits in most years. Animal rabies is more common in bats, raccoons, skunks, and foxes. The rarity, long incubation, and lack of routine testing make missed cases possible, especially when a donor dies suddenly and history is incomplete.

What Health Officials Advise Now

Hospitals and transplant centers are being urged to review records and watch for symptoms in recipients linked to the donor. Public health teams are also assessing whether surgical staff or family members need care.

  • Report any neurological symptoms in exposed patients immediately.
  • Consider rabies post-exposure prophylaxis when risk is identified.
  • Re-check donor history for animal bites or scratches, especially from bats or wild mammals.
  • Coordinate with local and state health departments for testing and vaccines.

Expert Views and Next Steps

Infectious disease specialists say this event highlights the need for clear donor histories and rapid communication. They caution against overreaction: organ transplants save lives daily, and rabies-linked transmissions remain very rare. Still, they support stronger screening questions about recent animal encounters and unexplained neurological signs.

Transplant organizations may revisit checklists that flag risk. Some programs already pause recovery if there is a report of a bat in a donor’s living space or a fresh bite or scratch from a wild animal. Others have set protocols for sending preserved tissue for specialized testing when any concern arises.

What To Watch

Officials will release more details once lab tests confirm the strain of the virus and the chain of transmission. Expect guidance on whether changes to donor screening are warranted and if recipients should receive preventive treatment even without symptoms. The public health message remains the same: report animal bites and scratches, seek care quickly, and vaccinate pets to reduce the spread in wildlife and communities.

This case is a reminder that even rare infections can pose a threat in transplant medicine. The focus now is on finding any linked patients, delivering care fast, and learning enough to make a similar event less likely in the future.

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